HEALTHY DYNAMICS OF CD4 T CELLS MAY DRIVE HIV RESURGENCE IN PERINATALLY-INFECTED INFANTS ON ANTIRETROVIRAL THERAPY.

Healthy dynamics of CD4 T cells may drive HIV resurgence in perinatally-infected infants on antiretroviral therapy.

In 2019 there were 490,000 children under five living with HIV.Understanding the dynamics of HIV suppression and rebound in this age group is crucial to optimizing treatment strategies and increasing the likelihood of infants achieving and sustaining viral suppression.Here we studied data from a cohort of 122 perinatally-infected infants who initia

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MAp34 Regulates the Non-specific Cell Immunity of Monocytes/Macrophages and Inhibits the Lectin Pathway of Complement Activation in a Teleost Fish

The lectin pathway of the complement system is one of the main components of innate immunity, which plays a pivotal role in the defense against infectious microorganisms and maintains immune homeostasis.However, its control mechanisms remain unclear in teleost fish.In this study, we described the identification and functional characterization of a

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